The truth may be puzzling. It may take some work to grapple with. It may be counterintuitive. It may contradict deeply held prejudices. It may not be consonant with what we desperately want to be true. But our preferences do not determine what's true. We have a method, and that method helps us to reach not absolute truth, only asymptotic approaches to the truth—never there, just closer and closer, always finding vast new oceans of undiscovered possibilities. Cleverly designed experiments are the key.

While reading in a textbook of chemistry, ... I came across the statement, 'nitric acid acts upon copper.' I was getting tired of reading such absurd stuff and I determined to see what this meant. Copper was more or less familiar to me, for copper cents were then in use. I had seen a bottle marked 'nitric acid' on a table in the doctor's office where I was then 'doing time.' I did not know its peculiarities, but I was getting on and likely to learn. The spirit of adventure was upon me. Having nitric acid and copper, I had only to learn what the words 'act upon' meant... I put one of them [cent] on the table, opened the bottle marked 'nitric acid'; poured some of the liquid on the copper; and prepared to make an observation. But what was this wonderful thing which I beheld? The cent was already changed, and it was no small change either. A greenish blue liquid foamed and fumed over the cent and over the table. The air in the neighborhood of the performance became colored dark red. A great colored cloud arose. This was disagreeable and suffocating—how should I stop this? I tried to get rid of the objectionable mess by picking it up and throwing it out of the window, which I had meanwhile opened. I learned another fact—nitric acid not only acts upon copper but it acts upon fingers. The pain led to another unpremeditated experiment. I drew my fingers across my trousers and another fact was discovered. Nitric acid acts upon trousers. Taking everything into consideration, that was the most impressive experiment, and, relatively, probably the most costly experiment I have ever performed.

As every circumstance relating to so capital a discovery as this (the greatest, perhaps, that has been made in the whole compass of philosophy, since the time of Sir Isaac Newton) cannot but give pleasure to all my readers, I shall endeavour to gratify them with the communication of a few particulars which I have from the best authority. The Doctor [Benjamin Franklin], after having published his method of verifying his hypothesis concerning the sameness of electricity with the matter lightning, was waiting for the erection of a spire in Philadelphia to carry his views into execution; not imagining that a pointed rod, of a moderate height, could answer the purpose; when it occurred to him, that, by means of a common kite, he could have a readier and better access to the regions of thunder than by any spire whatever. Preparing, therefore, a large silk handkerchief, and two cross sticks, of a proper length, on which to extend it, he took the opportunity of the first approaching thunder storm to take a walk into a field, in which there was a shed convenient for his purpose. But dreading the ridicule which too commonly attends unsuccessful attempts in science, he communicated his intended experiment to no body but his son, who assisted him in raising the kite.

The kite being raised, a considerable time elapsed before there was any appearance of its being electrified. One very promising cloud passed over it without any effect; when, at length, just as he was beginning to despair of his contrivance, he observed some loose threads of the hempen string to stand erect, and to avoid one another, just as if they had been suspended on a common conductor. Struck with this promising appearance, he inmmediately presented his knuckle to the key, and (let the reader judge of the exquisite pleasure he must have felt at that moment) the discovery was complete. He perceived a very evident electric spark. Others succeeded, even before the string was wet, so as to put the matter past all dispute, and when the rain had wetted the string, he collected electric fire very copiously. This happened in June 1752, a month after the electricians in France had verified the same theory, but before he had heard of any thing that they had done.

You all have learned reliance
On the sacred teachings of Science,
So I hope, through life, you will never decline
In spite of philistine Defiance
To do what all good scientists do.
Experiment.
Make it your motto day and night.
Experiment.
And it will lead you to the light.

Almost every major systematic error which has deluded men for thousands of years relied on practical experience. Horoscopes, incantations, oracles, magic, witchcraft, the cures of witch doctors and of medical practitioners before the advent of modern medicine, were all firmly established through the centuries in the eyes of the public by their supposed practical successes. The scientific method was devised precisely for the purpose of elucidating the nature of things under more carefully controlled conditions and by more rigorous criteria than are present in the situations created by practical problems.

The lessons of science should be experimental also. The sight of a planet through a telescope is worth all the course on astronomy; the shock of the electric spark in the elbow outvalues all theories; the taste of the nitrous oxide, the firing of an artificial volcano, are better than volumes of chemistry.

Natural science is founded on minute critical views of the general order of events taking place upon our globe, corrected, enlarged, or exalted by experiments, in which the agents concerned are placed under new circumstances, and their diversified properties separately examined. The body of natural science, then, consists of facts; is analogy,—the relation of resemblance of facts by which its different parts are connected, arranged, and employed, either for popular use, or for new speculative improvements.

It is well-known that those who have charge of young infants, that it is difficult to feel sure when certain movements about their mouths are really expressive; that is when they really smile. Hence I carefully watched my own infants. One of them at the age of forty-five days, and being in a happy frame of mind, smiled... I observed the same thing on the following day: but on the third day the child was not quite well and there was no trace of a smile, and this renders it probable that the previous smiles were real.

A famous experiment in high school physics involves putting an electric buzzer in a bell jar, a glass container from which the air can be removed by a pump. When the air is removed, the sound of the buzzer disappears. As early as the seventeenth century, it was recognized that sound needed some medium to travel in. In a vacuum, such as exists inside the bell jar, there is nothing to carry the sound waves, so you don't hear the buzzer inside. To be more specific, sound is a pressure wave, or disturbance, which moves as regions where the pressure is higher or lower than the average pressure propagate through a medium. Take away the medium, and there is no pressure to have a disturbance in. Incidentally, the bell jar example was at the origin of a mystery I discussed earlier, which was very important in the history of physics. For while you cannot hear the buzzer, you can still see it! Hence, if light is supposed to be some sort of wave, what medium does it travel in which isn't removed when you remove the air? This was one of the prime justifications for the postulation of the aether.

By no amount of reasoning can we altogether eliminate all contingency from our world. Moreover, pure speculation alone will not enable us to get a determinate picture of the existing world. We must eliminate some of the conflicting possibilities, and this can be brought about only by experiment and observation.